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A Los Angeles District Attorney (Gene Hackman) is attempting to take an unwilling murder witness (Anne Archer) back to the United States from Canada to testify against a top-level mob boss. Frantically attempting to escape two deadly hit men sent to silence her, they board a Vancouver-bound train only to find the killers are on board with them. For the next 20 hours, as the train hurls through the beautiful but isolated Canadian wilderness, a deadly game of cat and mouse ensues in which their ability to tell friend from foe is a matter of life and death.